Milk thistle meal Solnat 100g

Manufacturer: Natural oils, Russia

Dietary supplement Not a medicine.
Before use, it is recommended to consult a doctor (specialist).

Compound
Milk thistle extract (silymarin) + excipients

Milk thistle interacts with free radicals in the liver and reduces their toxicity. By interrupting the process of lipid peroxidation, it prevents further destruction of cellular structures.

In damaged hepatocytes, it stimulates the synthesis of structural and functional proteins and phospholipids (due to specific stimulation of RNA polymerase A), stabilizes cell membranes, prevents the loss of cellular components and intracellular enzymes (transaminases), and accelerates the regeneration of liver cells.

Inhibits the penetration of certain hepatotoxic substances (poisons of the toadstool fungus) into cells. Subject to enterohepatic circulation. Metabolized in the liver by conjugation. It is excreted mainly in bile in the form of glucuronides and sulfates, and to a small extent in urine.

Does not accumulate. After repeated oral administration of 140 mg 3 times a day, a stable concentration is achieved.

   Improves the general condition of patients with liver diseases, reduces subjective complaints, normalizes laboratory parameters (activity of transaminases, gamma-glutamyltransferase, alkaline phosphatase, bilirubin level).

Long-term use significantly increases the survival rate of patients suffering from liver cirrhosis.

Indications

     toxic liver damage (alcoholism, intoxication with halogenated hydrocarbons, heavy metal compounds, drug-induced liver damage) and their prevention;
     chronic hepatitis;
     liver cirrhosis (as part of complex therapy);
     conditions after infectious and toxic hepatitis; dystrophy and fatty infiltration of the liver;
     correction of lipid metabolism disorders.

Contraindications

Hypersensitivity

Side effects

     diarrhea;
     allergic reactions;
     children under 12 years of age;
     hypersensitivity to the components of the drug.

Interaction

When Milk Thistle is used together with oral hormonal contraceptives and medications intended for hormone replacement therapy, the effects of the latter may be reduced.

Silymarin can enhance the effects of diazepam, alprazolam, ketoconazole, lovastatin, vinblastine due to its inhibitory effect on microsomal enzymes of the cytochrome P450 system.

How to take, course of administration and dosage

Adults and children over 12 years of age take 1 teaspoon of powder (3.5 g) per day during meals with plenty of liquid.

Duration of treatment - 1 month.

Storage conditions
Store in a dry place, protected from light, at a temperature not exceeding +25°C.